SELPLG anticorps (C-Term)
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- Antigène Voir toutes SELPLG Anticorps
- SELPLG (Selectin P Ligand (SELPLG))
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Épitope
- C-Term
- Reactivité
- Humain, Rat, Boeuf (Vache), Chien, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SELPLG est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- EMVCISSLLP DGGEGPSATA NGGLSKAKSP GLTPEPREDR EGDDLTLHSF
- Homologie
- Cow: 91%, Dog: 83%, Guinea Pig: 92%, Human: 100%, Rat: 83%
- Attributs du produit
- This is a rabbit polyclonal antibody against SELPLG. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SELPLG
- Top Product
- Discover our top product SELPLG Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 412 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SELPLG (Selectin P Ligand (SELPLG))
- Autre désignation
- SELPLG (SELPLG Produits)
- Synonymes
- anticorps CD162, anticorps CLA, anticorps PSGL-1, anticorps PSGL1, anticorps SELPLG, anticorps SELPG, anticorps Psgl-1, anticorps Psgl1, anticorps Selp1, anticorps Selpl, anticorps selectin P ligand, anticorps selectin, platelet (p-selectin) ligand, anticorps clasper, anticorps SELPLG, anticorps Selplg, anticorps cla
- Sujet
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This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
Alias Symbols: CD162, CLA, PSGL-1, PSGL1
Protein Interaction Partner: MAGEA1, TNIP1, PIK3R1, GALNT4, BACE1, TPST2, TPST1, SELL, SYK, MSN, SELP, SELE, VCAN, CTSG, SELPLG,
Protein Size: 412 - Poids moléculaire
- 39 kDa
- ID gène
- 6404
- NCBI Accession
- NM_003006, NP_002997
- UniProt
- Q14242
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