RIN2 anticorps (N-Term)

N° du produit ABIN2790373

Détail du produit anti-RIN2 anticorps

Antigène: RIN2 (Ras and Rab Interactor 2 (RIN2))

Épitope: N-Term

Reactivité: Humain, Souris, Boeuf (Vache), Cheval, Porc, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIN2 est non-conjugé

Application: Western Blotting (WB)

Séquence: RTDVNLENGL EPAETHSMVR HKDGGYSEEE DVKTCARDSG YDSLSNRLSI

Homologie: Cow: 80%, Dog: 80%, Horse: 80%, Human: 100%, Mouse: 83%, Pig: 80%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against RIN2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human RIN2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RIN2

Antigène: RIN2 (Ras and Rab Interactor 2 (RIN2))

Autre désignation: RIN2 (RIN2 Produits)

Synonymes: anticorps RIN2, anticorps RINL, anticorps rassf4, anticorps MACS, anticorps RASSF4, anticorps 2010003K16Rik, anticorps 4632403N06Rik, anticorps AW821980, anticorps Ras and Rab interactor 2, anticorps Rin2, anticorps RIN2, anticorps rin2

Sujet: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.
Alias Symbols: MACS, RASSF4
Protein Size: 462

Poids moléculaire: 50 kDa

ID gène: 54453

NCBI Accession: NM_001242581, NP_001229510

UniProt: Q8WYP3