NKAP anticorps (C-Term)

N° du produit ABIN2790485

Détail du produit anti-NKAP anticorps

Antigène: NKAP (NFKB Activating Protein (NKAP))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cheval, Porc, Lapin, Boeuf (Vache), Chien, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKAP est non-conjugé

Application: Western Blotting (WB)

Séquence: EAVRLRKENQ IYSADEKRAL ASFNQEERRK RENKILASFR EMVYRKTKGK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against NKAP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NKAP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 415 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NKAP

Antigène: NKAP (NFKB Activating Protein (NKAP))

Autre désignation: NKAP (NKAP Produits)

Synonymes: anticorps DSMA4, anticorps GEF720, anticorps Syx, anticorps Tech, anticorps c6orf194l, anticorps wu:fj36d09, anticorps wu:fj49c09, anticorps 2610020O08Rik, anticorps AA987160, anticorps AI849147, anticorps AL024236, anticorps 2610020o08rik, anticorps nkap, anticorps NKAPL, anticorps NFKB activating protein, anticorps pleckstrin homology and RhoGEF domain containing G5, anticorps NFKB activating protein S homeolog, anticorps NKAP, anticorps PLEKHG5, anticorps nkap, anticorps Nkap, anticorps nkap.S

Sujet: This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
Alias Symbols: FLJ22626
Protein Interaction Partner: UBC, SRPK1, CSNK2A2, TTC14, FRA10AC1, NKAP, PRPF40A, RBMX2, DDX41, RBM39, PPIG, BUB3, PRPF3, U2AF1, PCBP2, DHX15, DHX8, CUL5, SUMO2, LUC7L2, CEP70, THAP1, FAM124A,
Protein Size: 415

Poids moléculaire: 46 kDa

ID gène: 79576

NCBI Accession: NM_024528, NP_078804

UniProt: Q8N5F7

Pathways: Stem Cell Maintenance, Phosphorylation & l'infection par le SRAS-CoV-2