IYD anticorps (N-Term)

N° du produit ABIN2790550

Détail du produit anti-IYD anticorps

Antigène: IYD (Iodotyrosine Deiodinase (IYD))

Épitope: N-Term

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IYD est non-conjugé

Application: Western Blotting (WB)

Séquence: NADRSMEKKK GEPRTRAEAR PWVDEDLKDS SDLHQAEEDA DEWQESEENV

Homologie: Cow: 77%, Dog: 79%, Human: 100%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against IYD. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IYD

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 247 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IYD

Antigène: IYD (Iodotyrosine Deiodinase (IYD))

Autre désignation: IYD (IYD Produits)

Synonymes: anticorps MGC85450, anticorps C6orf71, anticorps DEHAL1, anticorps TDH4, anticorps dJ422F24.1, anticorps 0610009A07Rik, anticorps AI265638, anticorps Dehal1, anticorps RGD1309288, anticorps IYD-1, anticorps iodotyrosine deiodinase, anticorps iodotyrosine deiodinase L homeolog, anticorps IYD, anticorps iyd.L, anticorps iyd, anticorps Iyd

Sujet: This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4.
Alias Symbols: C6orf71, DEHAL1, TDH4, dJ422F24.1
Protein Interaction Partner: TRIM69,
Protein Size: 247

Poids moléculaire: 27 kDa

ID gène: 389434

NCBI Accession: NM_001164695, NP_001158167

Pathways: Thyroid Hormone Synthesis