ATF7IP2 anticorps (N-Term)

N° du produit ABIN2790606

Détail du produit anti-ATF7IP2 anticorps

Antigène: ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF7IP2 est non-conjugé

Application: Western Blotting (WB)

Séquence: EEIVHSETKL EQVVCSYQKP SRTTESPSRV FTEEAKDSLN TSENDSEHQT

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ATF7IP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ATF7IP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 543 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATF7IP2

Antigène: ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))

Autre désignation: ATF7IP2 (ATF7IP2 Produits)

Synonymes: anticorps MCAF2, anticorps 4930558K11Rik, anticorps BC018510, anticorps Get-1, anticorps PSM2, anticorps activating transcription factor 7 interacting protein 2, anticorps ATF7IP2, anticorps Atf7ip2

Sujet: ATF7IP2 is a recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. It can both act as an activator or a repressor depending on the context. ATF7IP2 mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity.
Alias Symbols: FLJ12668, MCAF2
Protein Interaction Partner: SETDB1, SP1, MBD1,
Protein Size: 543

Poids moléculaire: 59 kDa

ID gène: 80063

NCBI Accession: NM_001256160, NP_001243089

UniProt: Q5U623