ATXN7L3 anticorps (Middle Region)

N° du produit ABIN2790607

Détail du produit anti-ATXN7L3 anticorps

Antigène: ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATXN7L3 est non-conjugé

Application: Western Blotting (WB)

Séquence: MNKSESDQED NDDINDNDWS YGSEKKAKKR KSDKLWYLPF QNPNSPRRSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ATXN7L3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human ATXN7L3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 354 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATXN7L3

Antigène: ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))

Autre désignation: ATXN7L3 (ATXN7L3 Produits)

Synonymes: anticorps E030022H21Rik, anticorps si:busm1-180g5.4, anticorps si:dz180g5.4, anticorps wu:fj12f07, anticorps zgc:136438, anticorps zgc:158566, anticorps ataxin 7 like 3, anticorps ataxin 7-like 3, anticorps ATXN7L3, anticorps Atxn7l3, anticorps atxn7l3

Sujet: ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Alias Symbols: DKFZp761G2113
Protein Interaction Partner: SIRT1, USP22, SECISBP2, SERTAD1, PICK1, USP6, UCHL3, HIST2H2BE, HIST2H2AC, ATXN7, KAT2A, ENY2, TAF5L, SUPT3H, TRRAP, TAF10,
Protein Size: 354

Poids moléculaire: 38 kDa

ID gène: 56970

NCBI Accession: NM_020218, NP_064603

UniProt: Q14CW9