YOD1 anticorps (N-Term)
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- Antigène Voir toutes YOD1 Anticorps
- YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))
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Épitope
- N-Term
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Reactivité
- Humain, Rat, Souris, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp YOD1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VPQSEAGTKA GPAGGRPADT MWRVRCKAKG GTHLLQGLSS RTRLRELQGQ
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against Yod1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Yod1
- Top Product
- Discover our top product YOD1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))
- Autre désignation
- Yod1 (YOD1 Produits)
- Synonymes
- anticorps DUBA8, anticorps OTUD2, anticorps PRO0907, anticorps hshin7, anticorps wu:fe01a10, anticorps zgc:112182, anticorps 9930028C20Rik, anticorps Hshin7, anticorps YOD1 deubiquitinase, anticorps YOD1 deubiquitinase L homeolog, anticorps YOD1, anticorps Yod1, anticorps yod1.L, anticorps yod1
- Sujet
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Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Yod1 may act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Yod1 mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. It is able to cleave both polyubiquitin and di-ubiquitin.
Alias Symbols: 9930028C20Rik, Hshin7
Protein Size: 343 - Poids moléculaire
- 37 kDa
- ID gène
- 226418
- NCBI Accession
- NM_178691, NP_848806
- UniProt
- Q8CB27
- Pathways
- ER-Nucleus Signaling
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