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PARPBP anticorps (C-Term)

PARPBP Reactivité: Humain, Cheval, Lapin, Porc, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2790948
  • Antigène Voir toutes PARPBP Anticorps
    PARPBP (PARP1 Binding Protein (PARPBP))
    Épitope
    • 8
    • 7
    • 7
    • 1
    C-Term
    Reactivité
    Humain, Cheval, Lapin, Porc, Rat
    Hôte
    • 15
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PARPBP est non-conjugé
    Application
    • 15
    • 12
    • 12
    • 12
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    YMENDLSEGV NPSVGRSTIG TSFGNVHLDR SKNEKVSRKS TSQTGNKSSK
    Homologie
    Horse: 85%, Human: 100%, Pig: 92%, Rabbit: 86%, Rat: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against PARPBP. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARPBP
    Top Product
    Discover our top product PARPBP Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PARPBP (PARP1 Binding Protein (PARPBP))
    Autre désignation
    PARPBP (PARPBP Produits)
    Synonymes
    anticorps C12orf48, anticorps PARI, anticorps PARPBP, anticorps AROM, anticorps C5H12orf48, anticorps PARP1BP, anticorps si:ch211-260p3.2, anticorps zgc:136263, anticorps c12orf48, anticorps 4930547N16Rik, anticorps AI503644, anticorps PARP1 binding protein, anticorps PARP1 binding protein L homeolog, anticorps PARPBP, anticorps Parpbp, anticorps parpbp, anticorps parpbp.L
    Sujet
    PARPBP is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. PARPBP antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. It binds single-strand DNA and poly(A) homopolymers and positively regulate the poly(ADP-ribosyl)ation activity of PARP1, however such function may be indirect.
    Protein Interaction Partner: UBC,
    Protein Size: 294
    Poids moléculaire
    32 kDa
    ID gène
    55010
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