PARPBP anticorps (C-Term)

N° du produit ABIN2790948

Détail du produit anti-PARPBP anticorps

Antigène: PARPBP (PARP1 Binding Protein (PARPBP))

Épitope: C-Term

Reactivité: Humain, Cheval, Lapin, Porc, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARPBP est non-conjugé

Application: Western Blotting (WB)

Séquence: YMENDLSEGV NPSVGRSTIG TSFGNVHLDR SKNEKVSRKS TSQTGNKSSK

Homologie: Horse: 85%, Human: 100%, Pig: 92%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PARPBP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARPBP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PARPBP

Antigène: PARPBP (PARP1 Binding Protein (PARPBP))

Autre désignation: PARPBP (PARPBP Produits)

Synonymes: anticorps C12orf48, anticorps PARI, anticorps PARPBP, anticorps AROM, anticorps C5H12orf48, anticorps PARP1BP, anticorps si:ch211-260p3.2, anticorps zgc:136263, anticorps c12orf48, anticorps 4930547N16Rik, anticorps AI503644, anticorps PARP1 binding protein, anticorps PARP1 binding protein L homeolog, anticorps PARPBP, anticorps Parpbp, anticorps parpbp, anticorps parpbp.L

Sujet: PARPBP is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. PARPBP antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. It binds single-strand DNA and poly(A) homopolymers and positively regulate the poly(ADP-ribosyl)ation activity of PARP1, however such function may be indirect.
Protein Interaction Partner: UBC,
Protein Size: 294

Poids moléculaire: 32 kDa

ID gène: 55010