EFTUD1 anticorps (N-Term)
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- Antigène Voir toutes EFTUD1 Anticorps
- EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Cheval, Lapin, Boeuf (Vache), Chien, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EFTUD1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KVLEERAERE TESQVNPNSE QGEQVYDWST GLEDTDDSHL YFSPEQGNVV
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against EFTUD1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human EFTUD1
- Top Product
- Discover our top product EFTUD1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1069 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))
- Autre désignation
- EFTUD1 (EFTUD1 Produits)
- Synonymes
- anticorps FAM42A, anticorps HsT19294, anticorps RIA1, anticorps 4932434J20Rik, anticorps 6030468D11Rik, anticorps AI451340, anticorps AU019507, anticorps AU022896, anticorps D7Ertd791e, anticorps elongation factor like GTPase 1, anticorps elongation factor like GPTase 1, anticorps EFL1, anticorps Efl1
- Sujet
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EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, EFTUD1 triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. EFTUD1 has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
Alias Symbols: FAM42A, HsT19294, RIA1
Protein Interaction Partner: TP53RK, FKBP10, RPRD1B, OSGEP, PANK4, NSUN2, UFM1, KIAA1279, ACTR2, TPD52L2, RANGAP1, LPP, BAG1, UBC,
Protein Size: 1069 - Poids moléculaire
- 117 kDa
- ID gène
- 79631
- NCBI Accession
- NM_001040610, NP_001035700
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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