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C1orf86 anticorps (C-Term)

C1ORF86 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2791345
  • Antigène Tous les produits C1orf86 (C1ORF86)
    C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))
    Épitope
    • 4
    • 1
    C-Term
    Reactivité
    • 5
    • 1
    Humain
    Hôte
    • 6
    Lapin
    Clonalité
    • 6
    Polyclonal
    Conjugué
    • 3
    • 1
    • 1
    • 1
    Cet anticorp C1orf86 est non-conjugé
    Application
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    ARSLPQRPAP DPCRAPRVEQ QPSVEGAAAL RSCPMCQKEF APRLTQLDVD
    Homologie
    Human: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against C1orf86. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human C1orf86
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 180 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))
    Autre désignation
    C1orf86 (C1ORF86 Produits)
    Synonymes
    anticorps FAAP20, anticorps FP7162, anticorps Fanconi anemia core complex associated protein 20, anticorps FAAP20
    Sujet
    C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
    Alias Symbols: FP7162
    Protein Interaction Partner: FANCL, FANCA, UBC, FANCC, APITD1, C19orf40, C17orf70, FANCM, REV1, FANCG, FANCF, FANCB, FANCE, ELAVL1,
    Protein Size: 180
    Poids moléculaire
    19 kDa
    ID gène
    199990
    NCBI Accession
    NM_182533, NP_872339
    UniProt
    Q6NZ36
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