anticorps CT12.1, anticorps CT12.1B, anticorps CTP9, anticorps GAGED2, anticorps XAGE-1, anticorps X antigen family member 1B, anticorps XAGE1B
Sujet
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. Alias Symbols: CT12.1, CT12.1B, CTP9, GAGED2 Protein Size: 160