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NSMCE4A anticorps (C-Term)
NSMCE4A
Reactivité: Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Lapin, Rat, Poisson zèbre (Danio rerio)
WB, IF
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2791705
Détail du produit anti-NSMCE4A anticorps
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Antigène
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NSMCE4A
(Non-SMC Element 4 Homolog A (NSMCE4A))
Épitope
Tous les épitopes à travers NSMCE4A Anticorps.
C-Term
Reactivité
Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Lapin, Rat, Poisson zèbre (Danio rerio)
Hôte
Toutes les hôtes sur NSMCE4A Anticorps
Lapin
Clonalité
Toutes les clonalités sur NSMCE4A Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers NSMCE4A Anticorps
Cet anticorp NSMCE4A est non-conjugé
Application
Tous les applications à travers NSMCE4A Anticorps.
Western Blotting (WB), Immunofluorescence (IF)
Séquence
PVIQEERAMP AQLRRMEESH QEATEKEVER ILGLLQTYFR EDPDTPMSFF
Homologie
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Attributs du produit
This is a rabbit polyclonal antibody against NSMCE4A. It was validated on Western Blot.
Purification
Affinity Purified
Immunogène
The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSMCE4A
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Information d'application
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Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeat freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur NSMCE4A
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Antigène
NSMCE4A
(Non-SMC Element 4 Homolog A (NSMCE4A))
Autre désignation
NSMCE4A (NSMCE4A Produits )
Synonymes
anticorps 2410003A14Rik, anticorps RGD1309025, anticorps C10orf86, anticorps NS4EA, anticorps NSE4A, anticorps NSE4 homolog A, SMC5-SMC6 complex component, anticorps Nsmce4a, anticorps NSMCE4A
Sujet
NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus. Alias Symbols: C10orf86, NS4EA, NSE4A Protein Interaction Partner: UBC, HECW2, SRPK2, SRPK1, MAGED4B, NDNL2, MAGEC2, MAGEH1, MAGED2, NDN, MAGEB1, MAGEA1, NSMCE1, SMC6, Protein Size: 385
Poids moléculaire
44 kDa
ID gène
54780
NCBI Accession
NM_017615 , NP_060085
UniProt
Q9NXX6
Pathways
Positive Regulation of Response to DNA Damage Stimulus
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