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NSMCE4A anticorps (C-Term)

NSMCE4A Reactivité: Humain, Souris, Lapin, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2791705
  • Antigène Voir toutes NSMCE4A Anticorps
    NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))
    Épitope
    • 8
    • 8
    • 7
    • 1
    • 1
    C-Term
    Reactivité
    Humain, Souris, Lapin, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval
    Hôte
    • 17
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp NSMCE4A est non-conjugé
    Application
    • 17
    • 12
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    PVIQEERAMP AQLRRMEESH QEATEKEVER ILGLLQTYFR EDPDTPMSFF
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against NSMCE4A. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSMCE4A
    Top Product
    Discover our top product NSMCE4A Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))
    Autre désignation
    NSMCE4A (NSMCE4A Produits)
    Synonymes
    anticorps 2410003A14Rik, anticorps RGD1309025, anticorps C10orf86, anticorps NS4EA, anticorps NSE4A, anticorps NSE4 homolog A, SMC5-SMC6 complex component, anticorps Nsmce4a, anticorps NSMCE4A
    Sujet
    NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
    Alias Symbols: C10orf86, NS4EA, NSE4A
    Protein Interaction Partner: UBC, HECW2, SRPK2, SRPK1, MAGED4B, NDNL2, MAGEC2, MAGEH1, MAGED2, NDN, MAGEB1, MAGEA1, NSMCE1, SMC6,
    Protein Size: 385
    Poids moléculaire
    44 kDa
    ID gène
    54780
    NCBI Accession
    NM_017615, NP_060085
    UniProt
    Q9NXX6
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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