PREX2 anticorps (N-Term)

N° du produit ABIN2791874

Détail du produit anti-PREX2 anticorps

Antigène: PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PREX2 est non-conjugé

Application: Western Blotting (WB)

Séquence: ERDYVGTLEF LVSAFLHRMN QCAASKVDKN VTEETVKMLF SNIEDILAVH

Homologie: Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PREX2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PREX2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PREX2

Antigène: PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))

Autre désignation: PREX2 (DEPDC2 Produits)

Synonymes: anticorps 6230420N16Rik, anticorps DEP.2, anticorps DEPDC2, anticorps P-REX2, anticorps AI316880, anticorps AI553603, anticorps C030045D06Rik, anticorps D430013K02, anticorps Depdc2, anticorps P-Rex2, anticorps phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2, anticorps phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2, anticorps PREX2, anticorps Prex2

Sujet: PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
Protein Interaction Partner: PPP1CA, MTOR, TGFBR1,
Protein Size: 1606

Poids moléculaire: 182 kDa

ID gène: 80243

UniProt: Q70Z35