NME1 anticorps (N-Term)

N° du produit ABIN2792090

Détail du produit anti-NME1 anticorps

Antigène: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NME1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Dot Blot (DB)

Séquence: ANCERTFIAI KPDGVQRGLV GEIIKRFEQK GFRLVGLKFM QASEDLLKEH

Homologie: Cow: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NME1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NME1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 152 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NME1

Antigène: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Autre désignation: NME1 (NME1 Produits)

Synonymes: anticorps AWD, anticorps GAAD, anticorps NB, anticorps NBS, anticorps NDKA, anticorps NDPK-A, anticorps NDPKA, anticorps NM23, anticorps NM23-H1, anticorps AL024257, anticorps NM23-M1, anticorps NM23A, anticorps NDPK-Z1, anticorps NM23-B, anticorps NM23-Z1, anticorps ndpkz1, anticorps nm23b, anticorps nme1, anticorps nme2, anticorps nme2b1, anticorps NME1, anticorps NME1-NME2, anticorps NM23-C1, anticorps ndpk-b, anticorps ndpkb, anticorps nm23-h2, anticorps nm23ndk, anticorps puf, anticorps NBR-A, anticorps NBR-B, anticorps NME1-1, anticorps nm23ndk-a, anticorps NDK I, anticorps NDPK I, anticorps T30A10.80, anticorps T30A10_80, anticorps NDP kinase I, anticorps NME/NM23 nucleoside diphosphate kinase 1, anticorps NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1, anticorps non-metastatic cells 1, protein (NM23A) expressed in, anticorps NME/NM23 nucleoside diphosphate kinase 2 S homeolog, anticorps NME/NM23 nucleoside diphosphate kinase 2 L homeolog, anticorps nucleoside diphosphate kinase, anticorps nucleoside diphosphate kinase 1, anticorps NME1, anticorps Nme1, anticorps nme2b.1, anticorps nme2.S, anticorps nme2.L, anticorps LOC547870, anticorps NDPK1, anticorps LOC107790563

Sujet: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alias Symbols: AWD, GAAD, NDPKA, NM23, NM23-H1, NB, NBS, NDKA, NDPK-A
Protein Interaction Partner: SREK1IP1, PID1, TNPO2, POLR1C, NME4, NME3, NME1, TUBG1, UBC, MDM2, ASB18, BMI1, CHRAC1, NME1-NME2, WDR1, THOP1, SORD, RBBP7, OXCT1, IDH1, FDPS, MAPK14, FBXO6, WDYHV1, NIF3L1, SOX30, FXR2, SMARCD1, NME2, CCND3, UROD, SOD1, MIF, ERG, EBNA-LP, HDAC5, STRAP,
Protein Size: 152

Poids moléculaire: 17 kDa

ID gène: 4830

NCBI Accession: NM_000269, NP_000260

UniProt: P22392

Pathways: Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process