RIPK3 anticorps (Middle Region)
-
- Antigène Voir toutes RIPK3 Anticorps
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
-
Épitope
- Middle Region
-
Reactivité
- Humain, Rat, Cheval, Chien
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp RIPK3 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- ETPGLEGLKE LMQLCWSSEP KDRPSFQECL PKTDEVFQMV ENNMNAAVST
- Homologie
- Dog: 92%, Horse: 92%, Human: 100%, Rat: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against RIPK3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human RIPK3
- Top Product
- Discover our top product RIPK3 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 518 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
Necroptosis mediated by receptor interacting protein kinase 3 as critical players in experimental congenital hypothyroidism related neuronal damage." dans: Northern clinics of Istanbul, Vol. 8, Issue 5, pp. 472-478, (2021) (PubMed).
: "
-
Necroptosis mediated by receptor interacting protein kinase 3 as critical players in experimental congenital hypothyroidism related neuronal damage." dans: Northern clinics of Istanbul, Vol. 8, Issue 5, pp. 472-478, (2021) (PubMed).
-
- Antigène
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
- Autre désignation
- RIPK3 (RIPK3 Produits)
- Synonymes
- anticorps RIPK3, anticorps RIP3, anticorps 2610528K09Rik, anticorps AW107945, anticorps Rip3, anticorps Hcyp2, anticorps receptor interacting serine/threonine kinase 3, anticorps receptor interacting serine/threonine kinase 3 S homeolog, anticorps receptor-interacting serine-threonine kinase 3, anticorps RIPK3, anticorps ripk3.S, anticorps Ripk3
- Sujet
-
RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RIP3
Protein Interaction Partner: BMH1, RFX6, FADD, RIPK1, CASP8, INPP5K, CDC37, STIP1, PYGL, FKBP5, FKBP4, CTNND1, UBC, XIAP, BIRC3, BIRC2, TICAM1, TRAF2, TNFRSF1A,
Protein Size: 518 - Poids moléculaire
- 57 kDa
- ID gène
- 11035
- NCBI Accession
- NM_006871, NP_006862
- UniProt
- Q9Y572
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
-