TIAL1 anticorps (C-Term)
-
- Antigène Voir toutes TIAL1 Anticorps
- TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
-
Épitope
- C-Term
-
Reactivité
- Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio), Cobaye
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp TIAL1 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- WNQQGFGVDQ SPSAAWMGGF GAQPPQGQAP PPVIPPPNQA GYGMASYQTQ
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%, Zebrafish: 76%
- Attributs du produit
- This is a rabbit polyclonal antibody against TIAL1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human TIAL1
- Top Product
- Discover our top product TIAL1 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 375 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
- Autre désignation
- TIAL1 (TIAL1 Produits)
- Synonymes
- anticorps TCBP, anticorps TIAR, anticorps 5330433G13Rik, anticorps AL033329, anticorps mTIAR, anticorps zgc:66130, anticorps tcbp, anticorps tiar, anticorps TIA1 cytotoxic granule associated RNA binding protein like 1, anticorps Tia1 cytotoxic granule-associated RNA binding protein-like 1, anticorps TIA1 cytotoxic granule-associated RNA binding protein-like 1, anticorps TIAL1, anticorps Tial1, anticorps tial1
- Sujet
-
The protein encoded by TIAL1 is a member of a family of RNA-binding proteins and possesses nucleolytic activity against cytotoxic lymphocyte target cells. The gene product is a cytotoxic granule-associated protein and has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. It has been suggested that members of this protein family may be involved in the induction of apoptosis. One isoform contains a lysosome-targeting motif in its C-terminal auxiliary domain, however, alternative splicing results in a T-cluster DNA-binding isoform, differing at the C-terminus where a hydrophobic sequence replaces the lysosome-targeting motif.
Alias Symbols: TCBP, TIAR
Protein Interaction Partner: SUMO2, UBC, RPA3, RPA2, RPA1, BMI1, SOX2, MAPK1, GADD45A, VCAM1, ITGA4, FN1, MRPL53, SARNP, UFM1, SBDS, MRPS28, TOMM40, ACAA2, GNB2L1, SF3B4, SCAMP3, SCO2, ALDH5A1, VDAC1, UBE2D2, THY1, SOD1, MBNL1, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CUL3, CUL4A, C
Protein Size: 375 - Poids moléculaire
- 42 kDa
- ID gène
- 7073
- NCBI Accession
- NM_003252, NP_003243
- UniProt
- Q01085
-