14-3-3 eta anticorps (N-Term)

N° du produit ABIN2792143

Détail du produit anti-14-3-3 eta anticorps

Antigène: 14-3-3 eta (YWHAH)

Épitope: N-Term

Reactivité: Humain, Lapin, Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 eta est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ADGNEKKLEK VKAYREKIEK ELETVCNDVL SLLDKFLIKN CNDFQYESKV

Homologie: Dog: 100%, Human: 100%, Rabbit: 100%, Zebrafish: 78%

Attributs du produit: This is a rabbit polyclonal antibody against YWHAH. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAH

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 246 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-14-3-3 eta (ABIN2792143)

Ubl, Berg, Holzmann, Krüger, Berger, Arzberger, Bornemann, Riess: "14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta." dans: Brain research. Molecular brain research, Vol. 108, Issue 1-2, pp. 33-9, (2002) (PubMed).

Détails sur 14-3-3 eta

Antigène: 14-3-3 eta (YWHAH)

Autre désignation: YWHAH (YWHAH Produits)

Synonymes: anticorps ywha1, anticorps 14-3-3e, anticorps YWHAH, anticorps YWHA1, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta L homeolog, anticorps YWHAH, anticorps ywhah, anticorps Ywhah, anticorps ywhah.L

Sujet: The YWHAH gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: YWHA1
Protein Interaction Partner: DTL, HUWE1, ABL1, SIK3, SUMO2, IRS4, CBL, UBC, UBFD1, EIF5, TBCB, CAPNS1, ALDH7A1, UBE2R2, ISOC1, FERMT2, YWHAQ, PDIA4, YWHAZ, YWHAG, YWHAE, XPO1, VCL, SNRPD2, PCYT2, PTMA, PAK2, PAFAH1B1, MYO1E, HNRNPK, HMGB3, GSS, GNAI3, G6PD, PPP1CA, MARK3, LRRK2, SAV1
Protein Size: 246

Poids moléculaire: 28 kDa

ID gène: 7533

NCBI Accession: NM_003405, NP_003396

UniProt: Q04917

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction