CDC25C anticorps (N-Term)
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- Antigène Voir toutes CDC25C Anticorps
- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDC25C est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- QKYEKLEKIG EGTYGTVFKA KNRETHEIVA LKRVRLDDDD EGVPSSALRE
- Homologie
- Human: 100%, Mouse: 91%, Rabbit: 83%
- Attributs du produit
- This is a rabbit polyclonal antibody against CDC25C. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CDC25C
- Top Product
- Discover our top product CDC25C Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 400 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
- Autre désignation
- CDC25C (CDC25C Produits)
- Synonymes
- anticorps CDC25C, anticorps cdc25, anticorps xcdc25c, anticorps CDC25, anticorps PPP1R60, anticorps Cdc25, anticorps cdc25-3, anticorps xcdc25-3, anticorps cell division cycle 25C, anticorps cell division cycle 25C S homeolog, anticorps CDC25C, anticorps cdc25c, anticorps Cdc25c, anticorps cdc25c.S
- Sujet
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CDC25C gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Alias Symbols: CDC25, PPP1R60
Protein Interaction Partner: CDC37, UBC, HSP90AA1, HSPA4, YWHAB, YWHAQ, YWHAZ, YWHAH, YWHAG, YWHAE, PKN1, SFN, MAPK9, PLK1, CHEK1, CHEK2, CDS1, MARK3, BRSK2, CDK2, PCNA, Cdk1, USP17L2, MAPK3, MAPK1, BRSK1, LZTS1, PLK3, NEDD4, PIN1, MAPK14, TP53, HRAS, LCK, CCNB1, CCNA2, SRC, SP1,
Protein Size: 400 - Poids moléculaire
- 45 kDa
- ID gène
- 995
- NCBI Accession
- NM_022809, NP_073720
- UniProt
- P30307
- Pathways
- Cycle Cellulaire, M Phase
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