RGS3 anticorps (C-Term)

N° du produit ABIN2792208

Cet anticorps Lapin Polyclonal détecte spécifiquement RGS3 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Cobaye et Lapin.

Aperçu rapide pour RGS3 anticorps (C-Term) (ABIN2792208)

Antigène: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RGS3 anticorps

Épitope: C-Term

Séquence: KDNLQSVTRG CFDLAQKRIF GLMEKDSYPR FLRSDLYLDL INQKKMSPPL

Specificité: Isoforms 1-4 & 6 of P49796

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RGS3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RGS3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 917 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RGS3

Antigène: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Autre désignation: RGS3

Sujet: RGS3 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.
Alias Symbols: C2PA, FLJ20370, FLJ31516, FLJ90496, PDZ-RGS3, RGP3
Protein Interaction Partner: GORASP2, UBC, PLSCR1, SUMO2, HES4, GNAI2, GNA11, APP, ACD, ARRB1, Nedd4, IRF5, ISG15, CNKSR2, PAX6, GLS2, YWHAE, HIPK3, PARK2, MAPK12, RGS3, YWHAB, YWHAZ, EFNB2, SCN5A, EFNB1, YWHAQ, GNAI3, GRIN2A, ESR1,
Protein Size: 917

Poids moléculaire: 101 kDa

ID gène: 5998

NCBI Accession: NM_130795, NP_570613

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling