RGS10 anticorps (Middle Region)

N° du produit ABIN2792213

Détail du produit anti-RGS10 anticorps

Antigène: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Épitope: Middle Region

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS10 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Séquence: DQIFNLMKYD SYSRFLKSDL FLKHKRTEEE EEDLPDAQTA AKRASRIYNT

Homologie: Cow: 81%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 90%, Rat: 90%

Attributs du produit: This is a rabbit polyclonal antibody against RGS10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RGS10

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 181 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RGS10

Antigène: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Autre désignation: RGS10 (RGS10 Produits)

Synonymes: anticorps MGC82511, anticorps RGS10, anticorps 2310010N19Rik, anticorps regulator of G-protein signaling 10, anticorps regulator of G-protein signaling 10 L homeolog, anticorps regulator of G protein signaling 10, anticorps regulator of G-protein signalling 10, anticorps RGS10, anticorps rgs10.L, anticorps rgs10, anticorps Rgs10

Sujet: RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G(I)-ALPHA and G(Z)- alpha but fails to interact with the structurally and functionally distinct G(S)-alpha subunit. Activity on G(Z)-alpha is inhibited by palmitoylation of the G-protein.
Protein Interaction Partner: UBC, ADRB2, APP, PRKACA, GNAI3, GNAO1, GNAI1, GNAZ, GNRHR, CALM1, ACP6, SAP18, EIF6,
Protein Size: 181

Poids moléculaire: 21 kDa

ID gène: 6001

NCBI Accession: NM_001005339, NP_001005339

UniProt: Q96GN0

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling