DEK anticorps (Middle Region)

N° du produit ABIN2792529

Détail du produit anti-DEK anticorps

Antigène: DEK (DEK Oncogene (DEK))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEK est non-conjugé

Application: Western Blotting (WB)

Séquence: ELKETIKKLL ASANLEEVTM KQICKKVYEN YPTYDLTERK DFIKTTVKEL

Réactivité croisée: Boeuf (Vache), Poulet, Humain, Souris, Rat (Rattus)

Homologie: Cow: 85%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 78%, Rabbit: 85%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against DEK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DEK

Information d'application

Indications d'application: WB Suggested Anti-DEK Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: MCF7 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 375 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DEK (ABIN2792529)

Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: "Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer." dans: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 378-83, (2008) (PubMed).

Détails sur DEK

Antigène: DEK (DEK Oncogene (DEK))

Autre désignation: DEK (DEK Produits)

Synonymes: anticorps D6S231E, anticorps DEK, anticorps 1810019E15Rik, anticorps D13H6S231E, anticorps DEK proto-oncogene, anticorps DEK proto-oncogene L homeolog, anticorps DEK oncogene (DNA binding), anticorps DEK oncogene, anticorps DEK, anticorps Dek, anticorps dek.L, anticorps LOC398543

Sujet: DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene and the presence of antibodies against this protein are all associated with various diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: D6S231E
Protein Interaction Partner: CUL3, SPOP, UBC, EED, IRF2BP2, GANAB, PTPN12, CSNK2A2, CSNK2A1, TP53BP1, ESR1, VTN, S100A9, RPL37A, DHX15, FTSJ3, WIBG, TMED9, EXOSC2, UTP14A, THRAP3, CAND1, COPS5, CDK2, YWHAZ, Cebpb, ELAVL1, SUMO1, SUMO2, RAD21, HDGF, KAT2B, EP300, CREBBP, HIST1H4A, HDA
Protein Size: 375

Poids moléculaire: 43 kDa

ID gène: 7913

NCBI Accession: NM_003472, NP_003463

UniProt: P35659