MAF anticorps (Middle Region)
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- Antigène Voir toutes MAF Anticorps
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Cheval, Chien, Cobaye, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAF est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LQQVDHLKQE ISRLVRERDA YKEKYEKLVS SGFRENGSSS DNPSSPEFFI
- Réactivité croisée
- Boeuf (Vache), Chien, Poulet, Humain, Souris, Rat (Rattus)
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 78%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against MAF. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human MAF
- Top Product
- Discover our top product MAF Anticorps primaire
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- Indications d'application
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WB Suggested Anti-MAF Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Hela cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Commentaires
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Antigen size: 403 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
- Autre désignation
- MAF (MAF Produits)
- Synonymes
- anticorps MAF, anticorps DKFZp459D1731, anticorps 2810401A20Rik, anticorps A230108G15Rik, anticorps AW047063, anticorps c-maf, anticorps CCA4, anticorps c-MAF, anticorps Maf2, anticorps cMaf, anticorps Z-cmaf, anticorps c-Maf, anticorps fl13d12, anticorps wu:fl13d12, anticorps C-Maf, anticorps MAF bZIP transcription factor, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian), anticorps avian musculoaponeurotic fibrosarcoma oncogene homolog, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a), anticorps MAF, anticorps Maf, anticorps mafa
- Sujet
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MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: MGC71685, c-MAF
Protein Interaction Partner: MAFB, FOSL1, MAF, FOS, ATF4, AHR, SUMO1, UBE2I, PML, SIN3A, HDAC2, SMARCA5, CEBPA, KDM5B, MAFA, SOX9, EP300, MAFG, USF2, CREBBP, MYB, JUN, ETS1, HOXD12,
Protein Size: 403 - Poids moléculaire
- 42 kDa
- ID gène
- 4094
- NCBI Accession
- NM_005360, NP_005351
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