DEK anticorps (N-Term)

N° du produit ABIN2792543

Détail du produit anti-DEK anticorps

Antigène: DEK (DEK Oncogene (DEK))

Épitope: N-Term

Reactivité: Humain, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEK est non-conjugé

Application: Western Blotting (WB)

Séquence: AAEGEGTPTQ PASEKEPEMP GPREESEEEE DEDDEEEEEE EKEKSLIVEG

Réactivité croisée: Boeuf (Vache), Humain, Rat (Rattus)

Homologie: Cow: 78%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Rabbit: 85%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against DEK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DEK

Information d'application

Indications d'application: WB Suggested Anti-DEK Antibody Titration: 1.25 µg/mL
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 375 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DEK (ABIN2792543)

Wang, Eckert, Zomorrodi, Xin, Pan, Shearer, Weisz, Maranus, Clawson: "Down-regulation of HtrA1 activates the epithelial-mesenchymal transition and ATM DNA damage response pathways." dans: PLoS ONE, Vol. 7, Issue 6, pp. e39446, (2012) (PubMed).

Détails sur DEK

Antigène: DEK (DEK Oncogene (DEK))

Autre désignation: DEK (DEK Produits)

Synonymes: anticorps D6S231E, anticorps DEK, anticorps 1810019E15Rik, anticorps D13H6S231E, anticorps DEK proto-oncogene, anticorps DEK proto-oncogene L homeolog, anticorps DEK oncogene (DNA binding), anticorps DEK oncogene, anticorps DEK, anticorps Dek, anticorps dek.L, anticorps LOC398543

Sujet: DEK was first identified in a fusion with the CAN nucleoporin protein in a specific subtype of acute myelogenous leukemia. DEK has also been shown to be an autoantigen in patients with pauciarticular onset juvenile rheumatoid arthritis. Further, the last 65 amino acids of DEK can partially reverse the mutation-prone phenotype of cells from patients with ataxia-telangiectasia
Alias Symbols: D6S231E
Protein Interaction Partner: CUL3, SPOP, UBC, EED, IRF2BP2, GANAB, PTPN12, CSNK2A2, CSNK2A1, TP53BP1, ESR1, VTN, S100A9, RPL37A, DHX15, FTSJ3, WIBG, TMED9, EXOSC2, UTP14A, THRAP3, CAND1, COPS5, CDK2, YWHAZ, Cebpb, ELAVL1, SUMO1, SUMO2, RAD21, HDGF, KAT2B, EP300, CREBBP, HIST1H4A, HDA
Protein Size: 375

Poids moléculaire: 43 kDa

ID gène: 7913

NCBI Accession: NM_003472, NP_003463

UniProt: P35659