SOX8 anticorps (C-Term)
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- Antigène Voir toutes SOX8 Anticorps
- SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SOX8 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ASPTETGPPR PHIKTEQPSP GHYGDQPRGS PDYGSCSGQS SATPAAPAGP
- Réactivité croisée
- Chien, Humain, Souris, Rat (Rattus)
- Homologie
- Cow: 92%, Dog: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 78%, Rat: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against SOX8. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8
- Top Product
- Discover our top product SOX8 Anticorps primaire
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- Indications d'application
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WB Suggested Anti-SOX8 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:12500
Positive Control: Hela cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Commentaires
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Antigen size: 446 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))
- Autre désignation
- SOX8 (SOX8 Produits)
- Synonymes
- anticorps SRY-box 8, anticorps SRY box 8, anticorps SRY-box 8 L homeolog, anticorps SRY (sex determining region Y)-box 8, anticorps SOX8, anticorps Sox8, anticorps sox8.L
- Sujet
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SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).
Alias Symbols: MGC24837
Protein Interaction Partner: JAM2, PIDD1, NOD1, UBC, MMP1, SOX2, HOXC11, UTF1, PAX3, OLIG2, HHEX, POU3F3, TCF12, DLX5, SP1, NR5A1, JUN, POU5F1, EGR2, CEBPA,
Protein Size: 446 - Poids moléculaire
- 47 kDa
- ID gène
- 30812
- NCBI Accession
- NM_014587, NP_055402
- UniProt
- P57073
- Pathways
- Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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