NF-kB p65 anticorps (N-Term)
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- Antigène Voir toutes NF-kB p65 (NFkBP65) Anticorps
- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Cheval, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NF-kB p65 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VEIIEQPKQR GMRFRYKCEG RSAGSIPGER STDTTKTHPT IKINGYTGPG
- Réactivité croisée
- Boeuf (Vache), Chien, Poulet, Humain, Souris, Porc, Rat (Rattus)
- Homologie
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against RELA. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human RELA
- Top Product
- Discover our top product NFkBP65 Anticorps primaire
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- Indications d'application
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WB Suggested Anti-RELA Antibody Titration: 1.0 µg/mL
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Commentaires
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Antigen size: 551 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
- Autre désignation
- RELA / NF-kB p65 (NFkBP65 Produits)
- Synonymes
- anticorps C-Rel, anticorps NFKB3, anticorps p65, anticorps NFkB, anticorps c-rel, anticorps zgc:100833, anticorps Xrel2, anticorps Xrel3, anticorps rel, anticorps rel-A, anticorps rel2, anticorps rel3, anticorps v-rel, anticorps xrel, anticorps REL proto-oncogene, NF-kB subunit, anticorps RELA proto-oncogene, NF-kB subunit, anticorps v-rel reticuloendotheliosis viral oncogene homolog A (avian), anticorps v-rel avian reticuloendotheliosis viral oncogene homolog, anticorps v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog, anticorps REL, anticorps RELA, anticorps Rela, anticorps Rel, anticorps rel, anticorps rel.L
- Sujet
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P65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex.
Alias Symbols: p65, NFKB3
Protein Interaction Partner: GAN, CCND1, ABCA1, UBC, TCF4, SRSF7, RELA, REL, PRKDC, PLG, PEX1, NFKB2, NFKB1, MUC3A, KRT5, REV1, TXN2, FBXW11, IL1RN, IKBKB, HSPA5, HDAC1, EP300, CREBBP, MAP3K8, CHEK1, CDKN2A, CDK4, SPATA31A3, POTEJ, POTEE, PIWIL4, DIS3L2, DCD, IKBKG, CHUK, PLA2G4A, ST
Protein Size: 551 - Poids moléculaire
- 60 kDa
- ID gène
- 5970
- NCBI Accession
- NM_021975, NP_068810
- UniProt
- Q04206
- Pathways
- Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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