GCM1 anticorps (C-Term)

N° du produit ABIN2792609

Détail du produit anti-GCM1 anticorps

Antigène: GCM1 (Glial Cells Missing Homolog 1 (GCM1))

Épitope: C-Term

Reactivité: Humain, Chien, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCM1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DFNSYVQSPA YHSPQEDPFL FTYASHPHQQ YSLPSKSSKW DFEEEMTYLG

Réactivité croisée: Chien, Humain

Homologie: Dog: 90%, Horse: 92%, Human: 100%, Rabbit: 81%

Attributs du produit: This is a rabbit polyclonal antibody against GCM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human GCM1

Information d'application

Indications d'application: WB Suggested Anti-GCM1 Antibody Titration: 0.2-1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 436 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GCM1 (ABIN2792609)

Drewlo, Czikk, Baczyk, Lye, Kingdom: "Glial cell missing-1 mediates over-expression of tissue inhibitor of metalloproteinase-4 in severe pre-eclamptic placental villi." dans: Human reproduction (Oxford, England), Vol. 26, Issue 5, pp. 1025-34, (2011) (PubMed).

Détails sur GCM1

Antigène: GCM1 (Glial Cells Missing Homolog 1 (GCM1))

Autre désignation: GCM1 / GCMA (GCM1 Produits)

Sujet: GCM1 is a DNA-binding protein with a gcm-motif (glial cell missing motif). GCM1 is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins.
Alias Symbols: GCMA, hGCMa
Protein Interaction Partner: FBXW2, UBC, SENP1, CAMK1, SUMO1, DUSP23, CREBBP, HDAC5, HDAC4, HDAC3, HDAC1, CUL1, SKP1, UBE2I,
Protein Size: 436

Poids moléculaire: 49 kDa

ID gène: 8521

NCBI Accession: NM_003643, NP_003634

UniProt: Q9NP62