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E2F5 anticorps (N-Term)

E2F5 Reactivité: Humain, Souris, Rat, Chien, Cobaye, Poisson zèbre (Danio rerio), Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2792655
  • Antigène Voir toutes E2F5 Anticorps
    E2F5
    Épitope
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 39
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Cobaye, Poisson zèbre (Danio rerio), Lapin
    Hôte
    • 36
    • 3
    Lapin
    Clonalité
    • 36
    • 3
    Polyclonal
    Conjugué
    • 17
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp E2F5 est non-conjugé
    Application
    • 28
    • 22
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    KAEIEDLELK ERELDQQKLL LQQSIKNVMD DSINNRFSYV THEDICNCFN
     Réactivité croisée
    Poulet, Humain, Souris, Rat (Rattus)
    Homologie
    Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 84%
    Attributs du produit
    This is a rabbit polyclonal antibody against E2F5. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human E2F5
    Top Product
    Discover our top product E2F5 Anticorps primaire
  • Indications d'application
    WB Suggested Anti-E2F5 Antibody Titration: 0.2-1 µg/mL
    Positive Control: Jurkat cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 346 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    E2F5
    Autre désignation
    E2F5 (E2F5 Produits)
    Synonymes
    anticorps AU024671, anticorps E2F-5, anticorps E2f-5, anticorps E2F4, anticorps cb735, anticorps zgc:111879, anticorps E2F transcription factor 5, anticorps E2f5, anticorps e2f5, anticorps E2F5
    Sujet
    E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It is more homologous to E2F4, a family member, than to other members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB.
    Alias Symbols: E2F-5
    Protein Interaction Partner: RBL2, UBC, KMT2D, BRCC3, SMAD3, EP300, XPO1, CREBBP, TFDP1, RBL1, BIRC5, MYC, MT1G,
    Protein Size: 346
    Poids moléculaire
    38 kDa
    ID gène
    1875
    NCBI Accession
    NM_001951, NP_001942
    UniProt
    Q15329
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