SUB1 anticorps (Middle Region)

N° du produit ABIN2792675

Détail du produit anti-SUB1 anticorps

Antigène: SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: NMFQIGKMRY VSVRDFKGKV LIDIREYWMD PEGEMKPGRK GISLNPEQWS

Réactivité croisée: Boeuf (Vache), Chien, Poulet, Humain, Souris, Rat (Rattus)

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PC4. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PC4

Information d'application

Indications d'application: WB Suggested Anti-PC4 Antibody Titration: 0.5-1.0 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 127 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SUB1

Antigène: SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))

Autre désignation: SUB1 / PC4 (SUB1 Produits)

Synonymes: anticorps P15, anticorps PC4, anticorps p14, anticorps AI842364, anticorps P9, anticorps Pc4, anticorps Rpo2tc1, anticorps SUB1 homolog, transcriptional regulator, anticorps SUB1 homolog (S. cerevisiae), anticorps SUB1, anticorps Sub1

Sujet: PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
Alias Symbols: P15, PC4, p14
Protein Interaction Partner: HUWE1, SUB1, UBC, rev, CLK4, CDK2, HNF4A, FN1, CSNK2A1, SMURF1, RPL18A, LAMP2, CDC5L, APP, YWHAZ, GTF3C1, ELAVL1, SUMO2, HDGF, Shoc2, Kif1c, POLR2B, POLR2A, CBX5, RCOR1, REST, BANF1, ADAP1, GTF2A1L, EP300, POU2AF1, CSTF2, TBP, TAF1, PCNA, HSF1, PSIP1, SP1
Protein Size: 127

Poids moléculaire: 14 kDa

ID gène: 10923

NCBI Accession: NM_006713, NP_006704

UniProt: P53999