P-Glycoprotein anticorps (Center)
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- Antigène Tous les produits P-Glycoprotein
- P-Glycoprotein
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Épitope
- AA 647-677, Center
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp P-Glycoprotein est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit Anti-Human P-Glycoprotein (ABCB1) (Center) Antibody
- Immunogène
- This P-Glycoprotein (ABCB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-677 amino acids from the Central region of human P-Glycoprotein (ABCB1).
- Isotype
- Ig Fraction
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- Indications d'application
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Western Blot
Recommended Dilutions
WB: 1:1000ABCB1 Antibody (L661) . - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2.000 mg/mL
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- Antigène
- P-Glycoprotein
- Abstract
- P-Glycoprotein Produits
- Synonymes
- anticorps ABC20, anticorps CD243, anticorps CLCS, anticorps GP170, anticorps MDR1, anticorps P-GP, anticorps PGY1, anticorps Abcb1, anticorps Mdr1a, anticorps ABCB1, anticorps ABCB4, anticorps CMDR1, anticorps xemdr, anticorps ATP binding cassette subfamily B member 1, anticorps ATP binding cassette subfamily B member 1A, anticorps ATP binding cassette subfamily B member 1 L homeolog, anticorps ABCB1, anticorps Abcb1a, anticorps abcb1.L
- Sujet
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Target Description: The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Gene Symbol: ABCB1
- Poids moléculaire
- 141479 Da
- ID gène
- 5243
- UniProt
- P08183
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