KDELR1 anticorps (C-Term)
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- Antigène Voir toutes KDELR1 Anticorps
- KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
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Épitope
- AA 185-211, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KDELR1 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit Anti-Human KDELR1 (C-term) Antibody
- Immunogène
- This KDELR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-211 amino acids from the C-terminal region of human KDELR1.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product KDELR1 Anticorps primaire
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- Indications d'application
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Western Blot
Recommended Dilutions
WB: 1:1000KDELR1 Antibody (C-term) . - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.470 mg/mL
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- Antigène
- KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
- Autre désignation
- KDELR1 (KDELR1 Produits)
- Synonymes
- anticorps ERD2, anticorps ERD2.1, anticorps HDEL, anticorps PM23, anticorps 8030486F04Rik, anticorps AW215843, anticorps Erd2.1, anticorps KDEL endoplasmic reticulum protein retention receptor 1, anticorps KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1, anticorps KDELR1, anticorps Kdelr1
- Sujet
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Target Description: Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.
Gene Symbol: KDELR1
- Poids moléculaire
- 24542 Da
- ID gène
- 10945
- UniProt
- P24390
- Pathways
- Maintenance of Protein Location
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