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HAT1 anticorps (C-Term)

HAT1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2797110
  • Antigène Voir toutes HAT1 Anticorps
    HAT1 (Histone Aminotransferase 1 (HAT1))
    Épitope
    • 2
    • 1
    • 1
    • 1
    AA 389-419, C-Term
    Reactivité
    Humain
    Hôte
    • 4
    Lapin
    Clonalité
    • 4
    Polyclonal
    Conjugué
    • 4
    Cet anticorp HAT1 est non-conjugé
    Application
    Western Blotting (WB)
    Fonction
    Rabbit Anti-Human KAT1 (HAT1) (C-term) Antibody
    Immunogène
    This KAT1 (HAT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the C-terminal region of human KAT1 (HAT1).
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HAT1 Anticorps primaire
  • Indications d'application
    Western Blot
    Recommended Dilutions
    WB: 1:1000Western blot analysis of hHAT1-E404 was detected using the purified Pab.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2.0 mg/mL
    Stock
    4 °C,-20 °C
    Stockage commentaire
    2-8°C (short-term), -20°C (long-term)
  • Antigène
    HAT1 (Histone Aminotransferase 1 (HAT1))
    Autre désignation
    KAT1 (HAT1 Produits)
    Synonymes
    anticorps GTK, anticorps KAT1, anticorps KATI, anticorps kynurenine aminotransferase 1, anticorps KYAT1
    Sujet

    Target Description: Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.

    Gene Symbol: HAT1

    Poids moléculaire
    49513 Da
    ID gène
    8520
    UniProt
    O14929
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