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TLR2 anticorps (N-Term)

TLR2 Reactivité: Humain WB, IHC, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2798860
  • Antigène Voir toutes TLR2 Anticorps
    TLR2 (Toll-Like Receptor 2 (TLR2))
    Épitope
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 212-242, N-Term
    Reactivité
    • 5
    • 5
    Humain
    Hôte
    • 6
    • 2
    Lapin
    Clonalité
    • 6
    • 2
    Polyclonal
    Conjugué
    • 7
    • 1
    Cet anticorp TLR2 est non-conjugé
    Application
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Fonction
    Rabbit Anti-Human TLR2 (N-term) Antibody
    Immunogène
    This TLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the N-terminal region of human TLR2.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TLR2 Anticorps primaire
  • Indications d'application
    Western Blot, Immunohistochemistry, Flow Cytometry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of hTLR2-C226 . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2.0 mg/mL
    Stock
    4 °C,-20 °C
    Stockage commentaire
    2-8°C (short-term), -20°C (long-term)
  • Antigène
    TLR2 (Toll-Like Receptor 2 (TLR2))
    Autre désignation
    TLR2 (TLR2 Produits)
    Synonymes
    anticorps CD282, anticorps TIL4, anticorps Ly105, anticorps toll like receptor 2, anticorps toll-like receptor 2, anticorps TLR2, anticorps Tlr2, anticorps tlr2
    Sujet

    Target Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

    Gene Symbol: TLR2

    Poids moléculaire
    89838 Da
    ID gène
    7097
    UniProt
    O60603
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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