NSG1 anticorps (AA 1-100) (AbBy Fluor® 594)
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- Antigène Voir toutes NSG1 (D4S234E) Anticorps
- NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
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Épitope
- AA 1-100
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Reactivité
- Souris, Singe
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NSG1 est conjugé à/à la AbBy Fluor® 594
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Singe, Souris
- Homologie
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human NEEP21
- Isotype
- IgG
- Top Product
- Discover our top product D4S234E Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
- Autre désignation
- NEEP21 (D4S234E Produits)
- Synonymes
- anticorps D4S234, anticorps D4S234E, anticorps NEEP21, anticorps P21, anticorps Neep21, anticorps m234, anticorps p21, anticorps Bsmrb, anticorps PEP1, anticorps neuronal vesicle trafficking associated 1, anticorps neuron specific gene family member 1, anticorps NSG1, anticorps Nsg1
- Sujet
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Synonyms: neuron-enriched endosomal 21 kDa protein, NSG1_HUMAN.
Background: NEEP21, also known as Brain neuron cytoplasmic protein 1, NSG1 (neuron-specific proteins family member 1), P21 or D4S234E, is a single pass type II membrane protein belonging to the NSG family. It is highly expressed during neuronal maturation but its expression is downregulated in adult tissues. NEEP21 predominantly localizes to Rab 4-positive early endosomes in the somatodendritic neuronal compartment and is essential for proper receptor sorting and recycling in neurons. It associates with GRIP1 and GluR-2 and mediates the surface expression of GluR-2. When this interaction is interrupted, GluR-2 accumulates in early endosomes and leads to changes in evoked synaptic current properties. In addition, NEEP21 forms a complex with the SNARE protein, Syntaxin 13 (also known as Syntaxin 12), and participates in the recycling of transferrin receptors (TFRs) and NTR2 (neurotensin receptor 2).
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