SPG21 anticorps (AA 151-250) (AbBy Fluor® 594)
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- Antigène Voir toutes SPG21 Anticorps
- SPG21 (Spastic Paraplegia 21 (SPG21))
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Épitope
- AA 151-250
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPG21 est conjugé à/à la AbBy Fluor® 594
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Homologie
- Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human SPG21
- Isotype
- IgG
- Top Product
- Discover our top product SPG21 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SPG21 (Spastic Paraplegia 21 (SPG21))
- Autre désignation
- SPG21 (SPG21 Produits)
- Synonymes
- anticorps ACP33, anticorps GL010, anticorps MAST, anticorps BM-019, anticorps C78576, anticorps D9Wsu18e, anticorps Maspardin, anticorps wu:fd07h02, anticorps zgc:73091, anticorps SPG21, maspardin, anticorps spastic paraplegia 21 (autosomal recessive, Mast syndrome), anticorps SPG21, maspardin S homeolog, anticorps SPG21, anticorps Spg21, anticorps spg21.S, anticorps spg21
- Sujet
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Synonyms: Acid cluster protein 33, ACP33, BM019, BM-019, GL010, MAST, Maspardin, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21 antibody, SPG21_HUMAN.
Background: Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome.
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