SUV39H1 anticorps (AA 211-310) (AbBy Fluor® 594)
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- Antigène Voir toutes SUV39H1 Anticorps
- SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))
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Épitope
- AA 211-310
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SUV39H1 est conjugé à/à la AbBy Fluor® 594
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Histone-lysine N-methyltransferase SUV39H1
- Isotype
- IgG
- Top Product
- Discover our top product SUV39H1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))
- Autre désignation
- SUV39H1 (SUV39H1 Produits)
- Synonymes
- anticorps H3-K9-HMTase 1, anticorps KMT1A, anticorps MG44, anticorps SUV39H, anticorps AI852103, anticorps AL022883, anticorps DXHXS7466e, anticorps mIS6, anticorps RGD1565028, anticorps kmt1a, anticorps suv39h, anticorps fe02c04, anticorps suv39h1, anticorps wu:fe02c04, anticorps zgc:101027, anticorps fe47h06, anticorps wu:fb18a10, anticorps wu:fe47h06, anticorps zgc:136593, anticorps suppressor of variegation 3-9 homolog 1, anticorps suppressor of variegation 3-9 homolog 1 (Drosophila), anticorps suppressor of variegation 3-9 homolog 1 L homeolog, anticorps suppressor of variegation 3-9 homolog 1a, anticorps suppressor of variegation 3-9 homolog 1b, anticorps SUV39H1, anticorps Suv39h1, anticorps suv39h1.L, anticorps suv39h1a, anticorps suv39h1b
- Sujet
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Synonyms: H3 K9 HMTase, H3 K9 HMTase1, H3-K9-HMTase 1, Histone H3 K9 methylation, Histone H3 Lys 9 methylation, Histone H3-K9 methyltransferase 1, Histone H3-K9 methyltransferase1, Histone lysine N methyltransferase H3 lysine 9 specic 1, Histone lysine N methyltransferase, H3 lysine 9 specic 1, Histone-lysine N-methyltransferase SUV39H1, KMT1 A, Lysine N methyltransferase 1A, Lysine N-methyltransferase 1A, MG44, mIS6, Position-effect variegation 3-9 homolog, Suvar3 9 homolog 1, Suvar3-9 homolog 1, Suppressor of variegation 3 9 homolog 1 Drosophila, Suppressor of variegation 3-9 homolog 1, SUV39 H1, SUV39H, SUV39H1, SUV91_HUMAN.
Background: SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus.
- ID gène
- 6839
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