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EYA1 anticorps (AA 231-330) (AbBy Fluor® 647)

EYA1 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN2807748
  • Antigène Voir toutes EYA1 Anticorps
    EYA1 (Eyes Absent Homolog 1 (EYA1))
    Épitope
    • 15
    • 14
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 231-330
    Reactivité
    • 34
    • 24
    • 8
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 44
    • 1
    • 1
    Lapin
    Clonalité
    • 46
    Polyclonal
    Conjugué
    • 19
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EYA1 est conjugé à/à la AbBy Fluor® 647
    Application
    • 27
    • 23
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EYA1
    Isotype
    IgG
    Top Product
    Discover our top product EYA1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    EYA1 (Eyes Absent Homolog 1 (EYA1))
    Autre désignation
    EYA1 (EYA1 Produits)
    Synonymes
    anticorps EYA1, anticorps bop, anticorps bor, anticorps XEya1, anticorps wu:fc13c10, anticorps zgc:100770, anticorps BOP, anticorps BOR, anticorps BOS1, anticorps EYA transcriptional coactivator and phosphatase 1, anticorps EYA transcriptional coactivator and phosphatase 1 L homeolog, anticorps EYA1, anticorps eya1, anticorps Eya1, anticorps eya1.L
    Sujet

    Synonyms: BOP, BOR, BOS1, OFC1, Eyes absent homolog 1, EYA1

    Background: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears. Together with SIX1, it plays an important role in hypaxial muscle development, in this it is functionally redundant with EYA2.

    ID gène
    2138
    UniProt
    Q99502
    Pathways
    Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus
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