GPRC5A anticorps (AA 1-33) (AbBy Fluor® 594)
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- Antigène Voir toutes GPRC5A Anticorps
- GPRC5A (G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))
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Épitope
- AA 1-33
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GPRC5A est conjugé à/à la AbBy Fluor® 594
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Application
- Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human RAI3
- Isotype
- IgG
- Top Product
- Discover our top product GPRC5A Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GPRC5A (G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))
- Autre désignation
- RAI3 (GPRC5A Produits)
- Synonymes
- anticorps GPCR5A, anticorps RAI3, anticorps RAIG1, anticorps Rai3, anticorps Raig1, anticorps G protein-coupled receptor class C group 5 member A, anticorps G protein-coupled receptor, family C, group 5, member A, anticorps G protein-coupled receptor, class C, group 5, member A, anticorps GPRC5A, anticorps Gprc5a
- Sujet
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Synonyms: G protein coupled receptor family C group 5 member A, G-protein coupled receptor family C group 5 member A, GPCR 5A, GPCR5A, Gprc 5a, Gprc5a, Orphan G protein coupling receptor PEIG 1, Orphan G protein coupling receptor PEIG1, Orphan G-protein-coupling receptor PEIG-1, RAI 3, RAI3_HUMAN, Raig 1, RAIG-1, Raig1, Retinoic acid induced 3, Retinoic acid induced gene 1 protein, Retinoic acid induced protein 3, Retinoic acid responsive, Retinoic acid responsive gene, Retinoic acid-induced gene 1 protein, Retinoic acid-induced protein 3.
Background: RAI3 is an transmembrane G-protein-coupled receptor that affects many essential biological processes including embryogenesis, cell growth, differentiation, and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer, and selective suppression of signals from RAI3 may have a place in breast cancer treatments.
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