GID8/C20orf11 anticorps (AbBy Fluor® 594)
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- Antigène Voir toutes GID8/C20orf11 (GID8) Anticorps
- GID8/C20orf11 (GID8) (GID Complex Subunit 8 Homolog (GID8))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GID8/C20orf11 est conjugé à/à la AbBy Fluor® 594
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human TWA1/C20orf11
- Isotype
- IgG
- Top Product
- Discover our top product GID8 Anticorps primaire
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GID8/C20orf11 (GID8) (GID Complex Subunit 8 Homolog (GID8))
- Autre désignation
- C20orf11 (GID8 Produits)
- Synonymes
- anticorps C20orf11, anticorps TWA1, anticorps Bwk1, anticorps 2310003C23Rik, anticorps C13H20orf11, anticorps GID complex subunit 8 homolog, anticorps GID complex subunit 8, anticorps GID8, anticorps Gid8
- Sujet
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Synonyms: Chromosome 20 open reading frame 11, CT011_HUMAN, Protein C20orf11, Twa1, Two hybrid associated protein 1, Two hybrid-associated protein 1 with Ran BP-M, Two hybrid associated protein 1 with RanBPM, Two hybrid-associated protein 1 with RanBPM.
Background: TWA1 is a 228 amino acid nuclear protein that is highly conserved throughout evolution. TWA1 interacts with Ran BP-M, a protein that is implicated in a diverse array of cellular processes including DNA replication, entry into and exit from mitosis, and the transport of RNA and proteins through the nuclear pore complex. Together, Ran BP-M and TWA1 form a complex with cytoplasmic Muskelin, a mediator of cell spreading. It is thought that this complex plays a role in the Ran GTPase cycle and therefore a potential role in the cell cycle. TWA1 contains a LisH-CTLH motif which is usually found in proteins that are involved in nucleokinesis, chromosome segregation, cell migration and microtubule dynamics. The gene encoding TWA1 maps to human chromosome 20, which comprises approximately 2 % of the human genome and contains nearly 63 million bases that encode over 600 genes.
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