DERL1 anticorps (AA 111-220) (AbBy Fluor® 594)
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- Antigène Voir toutes DERL1 Anticorps
- DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
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Épitope
- AA 111-220
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DERL1 est conjugé à/à la AbBy Fluor® 594
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain
- Homologie
- Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DERLIN-1
- Isotype
- IgG
- Top Product
- Discover our top product DERL1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
- Autre désignation
- DERLIN-1 (DERL1 Produits)
- Synonymes
- anticorps CG10908, anticorps Dmel\\CG10908, anticorps DDBDRAFT_0188135, anticorps DDBDRAFT_0266772, anticorps DDB_0188135, anticorps DDB_0266772, anticorps MGC84200, anticorps wu:fb09d07, anticorps wu:fb94d05, anticorps wu:fj92g12, anticorps zgc:55637, anticorps 1110021N07Rik, anticorps AI195141, anticorps AW551338, anticorps Derlin-1, anticorps derlin-1, anticorps DER-1, anticorps DER1, anticorps RGD1311835, anticorps DERLIN-1, anticorps F17A13.150, anticorps F17A13_150, anticorps Derlin-1, anticorps derlin-1, anticorps derlin-1.1, anticorps hypothetical protein, anticorps Der1-like domain family, member 1, anticorps derlin 1, anticorps derlin 1 L homeolog, anticorps DERLIN-1, anticorps Der-1, anticorps EDI_023440, anticorps PTRG_01331, anticorps derl1, anticorps DERL1, anticorps derl1.L, anticorps Derl1, anticorps DER1
- Sujet
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Synonyms: Derlin1, Derlin1, Derlin 1, DER1, DER-1, DER 1, DERL1_HUMAN.
Background: Degradation in endoplasmic reticulum proteins, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins. Derlin proteins are multi-pass membrane proteins localizing to the ER. Derlins are involved in transferring misfolded proteins from the ER to the cytosol, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome. In the case of cytomegalovirus infection, Derlin-1, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11. Derlins may also be important for cell proliferation.
- ID gène
- 79139
- UniProt
- Q9BUN8
- Pathways
- ER-Nucleus Signaling
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