Estrogen Receptor alpha anticorps (pTyr537) (AbBy Fluor® 594)

N° du produit ABIN2812935

Détail du produit anti-Estrogen Receptor alpha anticorps (AbBy Fluor® 594)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Épitope: pTyr537

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Estrogen Receptor alpha est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human ER alpha around the phosphorylation site of Tyr537

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: Estrogen Receptor alpha (ESR1 Produits)

Synonymes: anticorps LOC398734, anticorps AA420328, anticorps AU041214, anticorps ER-alpha, anticorps ER[a], anticorps ERa, anticorps ERalpha, anticorps ESR, anticorps Estr, anticorps Estra, anticorps Nr3a1, anticorps NR3A1, anticorps eralpha, anticorps zfER[a], anticorps ER, anticorps ESRA, anticorps ESTRR, anticorps Era, anticorps akap12, anticorps cb27, anticorps esr1, anticorps fb72g12, anticorps id:ibd1202, anticorps sb:cb27, anticorps si:ch73-192g21.1, anticorps wu:fb72g12, anticorps wu:fc21c03, anticorps Esr, anticorps RNESTROR, anticorps ERALPHA, anticorps er, anticorps esr, anticorps nr3a1, anticorps XER, anticorps era, anticorps esra, anticorps ERbeta, anticorps xesr-1, anticorps xlERalpha1, anticorps xlERalpha2, anticorps ESR1, anticorps estrogen receptor 1 L homeolog, anticorps estrogen receptor 1 (alpha), anticorps estrogen receptor 1, anticorps A kinase (PRKA) anchor protein 12b, anticorps esr1.L, anticorps Esr1, anticorps ESR1, anticorps esr1, anticorps akap12b

Sujet:

Synonyms: ER alpha Tyr537, ER alpha Y537, ER alpha Y537, ER alpha Tyr537, p-ER alpha Tyr537, p-ER alpha Y537, Estrogen Receptor alpha Y537, Estrogen Receptor alpha Tyr537, Estradiol receptor, Estrogen receptor alpha, Estradiol Receptor-alpha, Estrogen Receptor 1, Atherosclerosis, susceptibility to, included, DKFZp686N23123, ER Alpha, ER, ER-alpha, ERalpha, ER[a], Era, ESR, ESR1, ESR1_HUMAN, ESR2, ESRA, Estr, Estrogen receptor 1 alpha, Estrogen resistance, included, HDL cholesterol, augmented response of, to hormone replacement, included, Myocardial infarction, susceptibility to, included, NR3A1, Nuclear receptor subfamily 3 group A member 1, OTTHUMP00000017718, OTTHUMP00000017719, RNESTROR.

Background: Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER Alpha and ER Beta. ER Alpha and ER Beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.

ID gène: 2099

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly