Klotho anticorps (C-Term)

N° du produit ABIN389493

Détail du produit anti-Klotho anticorps

Antigène: Klotho (KL)

Épitope: AA 986-1012, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Klotho est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Specificité: This Klotho antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 983~1012 amino acids from the C-terminal region of human Klotho.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Klotho antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 986-1012 AA from the C-terminal region of human Klotho.

Clone: RB21226

Isotype: Ig Fraction

Information d'application

Indications d'application: WB = 1:1000, FACS = 1:10-50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Klotho (ABIN389493)

Cheng, Chen, Cheng: "Decrease of Klotho in the kidney of streptozotocin-induced diabetic rats." dans: Journal of biomedicine & biotechnology, Vol. 2010, pp. 513853, (2010) (PubMed).

Détails sur Klotho

Antigène: Klotho (KL)

Autre désignation: Klotho (KL Produits)

Synonymes: anticorps alpha-kl, anticorps KL, anticorps LOC100223456, anticorps klotho, anticorps Klotho, anticorps KL, anticorps Kl, anticorps kl, anticorps LOC100533542

Sujet: Klotho is a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
Synonyms: Klotho, Klotho peptide, KL

Poids moléculaire: 116181 DA

ID gène: 9365

UniProt: Q9UEF7

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding