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RUNX2 anticorps (pSer465)

RUNX2 Reactivité: Humain DB Hôte: Lapin Polyclonal RB15321 unconjugated
N° du produit ABIN389942
  • Antigène Voir toutes RUNX2 Anticorps
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    Épitope
    • 16
    • 16
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer465
    Reactivité
    • 115
    • 46
    • 30
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 105
    • 12
    Lapin
    Clonalité
    • 98
    • 19
    Polyclonal
    Conjugué
    • 59
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RUNX2 est non-conjugé
    Application
    • 92
    • 46
    • 31
    • 25
    • 11
    • 9
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Dot Blot (DB)
    Specificité
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S533 of human RUNX2.
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This RUNX2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S465 of human RUNX2.
    Clone
    RB15321
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RUNX2 Anticorps primaire
  • Indications d'application
    DB = 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Fu, Wang, Lu, Ma, Ke, Liu, Luo: "In vitro inhibitory effects of terpenoids from Chloranthus multistachys on epithelial-mesenchymal transition via down-regulation of Runx2 activation in human breast cancer." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 22, Issue 1, pp. 165-72, (2015) (PubMed).

    Wang, Cai, Ma, Liu, Ke, Lu, Fu: "The natural compound codonolactone impairs tumor induced angiogenesis by downregulating BMP signaling in endothelial cells." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 22, Issue 11, pp. 1017-26, (2015) (PubMed).

    Fu, Ke, Tan, Liu, Wang, Ma, Lu: "The natural compound codonolactone attenuates TGF-?1-mediated epithelial-to-mesenchymal transition and motility of breast cancer cells." dans: Oncology reports, (2015) (PubMed).

    Wang, Chen, Zou, Tu, Tan, Lu, Liu, Fu: "Codonolactone, a sesquiterpene lactone isolated from Chloranthus henryi Hemsl, inhibits breast cancer cell invasion, migration and metastasis by downregulating the transcriptional activity of Runx2." dans: International journal of oncology, Vol. 45, Issue 5, pp. 1891-900, (2014) (PubMed).

    Tsimbouri, Murawski, Hamilton, Herzyk, Oreffo, Gadegaard, Dalby: "A genomics approach in determining nanotopographical effects on MSC phenotype." dans: Biomaterials, Vol. 34, Issue 9, pp. 2177-84, (2013) (PubMed).

    Tsimbouri, McMurray, Burgess, Alakpa, Reynolds, Murawski, Kingham, Oreffo, Gadegaard, Dalby: "Using nanotopography and metabolomics to identify biochemical effectors of multipotency." dans: ACS nano, Vol. 6, Issue 11, pp. 10239-49, (2012) (PubMed).

    McNamara, Sjöström, Burgess, Kim, Liu, Gordonov, Moghe, Meek, Oreffo, Su, Dalby: "Skeletal stem cell physiology on functionally distinct titania nanotopographies." dans: Biomaterials, Vol. 32, Issue 30, pp. 7403-10, (2011) (PubMed).

    Tetsunaga, Nishida, Furumatsu, Naruse, Hirohata, Yoshida, Saito, Ozaki: "Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells." dans: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 19, Issue 2, pp. 222-32, (2011) (PubMed).

  • Antigène
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    Autre désignation
    RUNX2 (RUNX2 Produits)
    Sujet
    Synonyms: Runt-related transcription factor 2, Core-binding factor subunit alpha-1, CBF-alpha-1, Acute myeloid leukemia 3 protein, Oncogene AML-3, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEBP2-alpha A, PEA2-alpha A, SL3-3 enhancer factor 1 alpha A
    Poids moléculaire
    56648 DA
    ID gène
    860
    UniProt
    Q13950
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