BCL3 anticorps (Center)

N° du produit ABIN653286

Détail du produit anti-BCL3 anticorps

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Épitope: AA 249-277, Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248~277 amino acids from the Center region of human BCL3.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 AA from the Central region of human BCL3.

Clone: RB23954

Isotype: Ig Fraction

Information d'application

Indications d'application: WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-BCL3 (ABIN653286)

Gehrke, Wörns, Huber, Hess, Straub, Hövelmeyer, Waisman, Kim, Schuppan, Galle, Schattenberg: "Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors." dans: Journal of hepatology, Vol. 65, Issue 6, pp. 1188-1197, (2018) (PubMed).

Détails sur BCL3

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Autre désignation: BCL3 (BCL3 Produits)

Synonymes: anticorps BCL3, anticorps AI528691, anticorps Bcl-3, anticorps BCL4, anticorps D19S37, anticorps B-cell CLL/lymphoma 3, anticorps B cell leukemia/lymphoma 3, anticorps BCL3, anticorps Bcl3

Sujet: BCL3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.
Synonyms: Proto-oncogene BCL3, B-cell lymphoma 3 protein, BCL-3, D19S37, BCL4, BCL3

Poids moléculaire: 46800 Da

ID gène: 602

UniProt: P20749

Pathways: Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus