EGF anticorps (Center)

N° du produit ABIN656805

Détail du produit anti-EGF anticorps

Antigène: EGF (Epidermal Growth Factor (EGF))

Épitope: AA 690-720, Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 689-720 amino acids from the Central region of human EGF.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-720 AA from the Central region of human EGF.

Clone: RB16555

Isotype: Ig Fraction

Information d'application

Indications d'application: WB = 1:1000, IHC (p) = 1:10-50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: EGF Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur EGF

Antigène: EGF (Epidermal Growth Factor (EGF))

Autre désignation: EGF (EGF Produits)

Sujet: This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
Synonyms: Pro-epidermal growth factor,EGF,

Poids moléculaire: 133994 DA

ID gène: 1950

NCBI Accession: NP_001954

UniProt: P01133

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation