EGF anticorps (Center)
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- Antigène Voir toutes EGF Anticorps
- EGF (Epidermal Growth Factor (EGF))
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Épitope
- AA 690-720, Center
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EGF est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 689-720 amino acids from the Central region of human EGF.
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-720 AA from the Central region of human EGF.
- Clone
- RB16555
- Isotype
- Ig Fraction
- Top Product
- Discover our top product EGF Anticorps primaire
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- Indications d'application
- WB = 1:1000, IHC (p) = 1:10-50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- EGF Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- EGF (Epidermal Growth Factor (EGF))
- Autre désignation
- EGF (EGF Produits)
- Sujet
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This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
Synonyms: Pro-epidermal growth factor,EGF, - Poids moléculaire
- 133994 DA
- ID gène
- 1950
- NCBI Accession
- NP_001954
- UniProt
- P01133
- Pathways
- Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
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