Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
B, M, Rat, X
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This TARBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human TARBP2.
anticorps trbp, anticorps trbp1, anticorps trbp2, anticorps MGC97783, anticorps TARBP2, anticorps LOQS, anticorps TRBP, anticorps TRBP1, anticorps TRBP2, anticorps fj51e12, anticorps wu:fj51e12, anticorps zgc:63778, anticorps Prbp, anticorps TAR (HIV-1) RNA binding protein 2, anticorps TARBP2, RISC loading complex RNA binding subunit, anticorps TAR (HIV-1) RNA binding protein 2 L homeolog, anticorps TAR (HIV) RNA binding protein 2, anticorps tarbp2, anticorps TARBP2, anticorps tarbp2.L, anticorps Tarbp2
Sujet
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.