NLRP2 anticorps

N° du produit ABIN363311

Détail du produit anti-NLRP2 anticorps

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Reactivité: Humain, Souris, Hamster, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificité: Reacts with NBS1 from human, mouse, hamster and primate

Purification: Antiserum

Immunogène: Partial length human NBS1 protein [Swiss-Prot# O60934].

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC : 1/50 to 1/200 - IF : 1/200 - IP : 3 μL - WB : 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: , Sodium azide 0.02 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Détails sur NLRP2

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Autre désignation: Nijmegen Breakage Syndrome 1 (NBS1) (NLRP2 Produits)

Synonymes: anticorps CLR19.9, anticorps NALP2, anticorps NBS1, anticorps PAN1, anticorps PYPAF2, anticorps NLRP2, anticorps E330007A02Rik, anticorps Nalp2, anticorps NLR family pyrin domain containing 2, anticorps NACHT, LRR and PYD domains-containing protein 2, anticorps NLR family pyrin domain containing 7, anticorps NLR family, pyrin domain containing 2, anticorps NLRP2, anticorps LOC100301026, anticorps LOC100387349, anticorps NLRP7, anticorps Nlrp2

Sujet: The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex.This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome