Cyclin A anticorps (Biotin)
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- Antigène Voir toutes Cyclin A (CCNA2) Anticorps
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Cyclin A est conjugé à/à la Biotin
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Specificité
- This antibody reacts with Cyclin A (55 kDa).
- Purification
- Protein-A Agarose Chromatography of hybridoma supernatant.
- Immunogène
- Bovine recombinant Cyclin A.
- Clone
- E67-1
- Isotype
- IgG2a
- Top Product
- Discover our top product CCNA2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 20 µg/mL
- Buffer
- PBS, pH 7.2 containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody (in aliquots) at -20 °C.
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- Antigène
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
- Autre désignation
- Cyclin A2 (CCNA2 Produits)
- Synonymes
- anticorps CCN1, anticorps CCNA, anticorps AA408589, anticorps Ccn-1, anticorps Ccn1, anticorps Ccna, anticorps CycA2, anticorps Cyca, anticorps cb671, anticorps chunp6924, anticorps wu:fi36f03, anticorps CYCA, anticorps Cyclin-A2, anticorps ccna2, anticorps ccn1, anticorps ccna, anticorps ccna1, anticorps Cyclin-A, anticorps cyclinA, anticorps cyclin A2, anticorps cyclin A2 S homeolog, anticorps cyclin A2 L homeolog, anticorps CCNA2, anticorps Ccna2, anticorps ccna2, anticorps ccna2.S, anticorps ccna2.L
- Sujet
- Cyclin A is a 60 kDa cyclin that binds both cdk2 and p34cdc2 (cdk1), giving two distinct cyclin A kinase activities, one appearing in G1/S phase, the other in G2/M. The level of cyclin A protein peaks in S-phase, and the activity of the cdk2-cyclin A complexes is essential for DNA replication and progression through S phase. Cyclin A is thus a marker for actively proliferating cells and for cells in S-phase. In normal cells, cdk2-cyclin A complexes associate with PCNA and p21CIPP1/WAF1. In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcrIPPtion factors DRT F1 and E2F, and retinoblastoma protein, p110.Synonyms: CCN1, CCNA, CCNA2, Cyclin A, Cyclin-A2
- ID gène
- 890
- NCBI Accession
- NP_001228
- UniProt
- P20248
- Pathways
- Signalisation PI3K-Akt, Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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