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FOXP3 anticorps (Biotin)

FOXP3 Reactivité: Souris FACS, IHC (fro) Hôte: Rat Monoclonal MF-14 Biotin
N° du produit ABIN2853612
  • Antigène Voir toutes FOXP3 Anticorps
    FOXP3 (Forkhead Box P3 (FOXP3))
    Reactivité
    • 163
    • 122
    • 51
    • 26
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 112
    • 68
    • 19
    • 2
    Rat
    Clonalité
    • 113
    • 88
    Monoclonal
    Conjugué
    • 89
    • 19
    • 14
    • 13
    • 10
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FOXP3 est conjugé à/à la Biotin
    Application
    • 131
    • 91
    • 70
    • 38
    • 38
    • 27
    • 27
    • 18
    • 16
    • 16
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    This antibody reacts with mouse Foxp3.
    Purification
    Protein G agarose
    Clone
    MF-14
    Isotype
    IgG2b
    Top Product
    Discover our top product FOXP3 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    PBS containing 1 % BSA and 0.09 % NaN3
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8 °C.
  • Antigène
    FOXP3 (Forkhead Box P3 (FOXP3))
    Autre désignation
    FOXP3 (FOXP3 Produits)
    Synonymes
    anticorps foxp3, anticorps FOXP3, anticorps AIID, anticorps DIETER, anticorps IPEX, anticorps PIDX, anticorps XPID, anticorps JM2, anticorps scurfin, anticorps sf, anticorps RGD1562112, anticorps forkhead box P3, anticorps forkhead box P3a, anticorps forkhead box P3 L homeolog, anticorps FOXP3, anticorps foxp3a, anticorps foxp3, anticorps foxp3.L, anticorps Foxp3
    Sujet
    Forkhead-winged helix P3 (Foxp3), also known as Scurfin or JM2, is a 50-55 kDa transcription factor, originally identified as the gene defective in Scurfy mice. Scurfy mice and humans with similar mutations spontaneously develop autoimmune diseases (IPEX). Resent reports revealed that Foxp3 is expressed in CD4 + CD25 + regulatory T cells (Treg cells), and ectopic expression of Foxp3 in CD4 + Foxp3 - T cells induced a Treg-like phenotype in these cells. Importantly, these reports indicate that Foxp3 is a specific marker for Treg cells. Taken together, Foxp3 is believed to be a crucial regulator of the development and function of Treg cells.Synonyms: Forkhead box protein P3, IPEX, JM2, Scurfin
    ID gène
    20371
    NCBI Accession
    NP_001186276
    UniProt
    Q99JB6
    Pathways
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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