ZAK anticorps

N° du produit ABIN2854433

Détail du produit anti-ZAK anticorps

Antigène: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZAK est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to ZAK
ZAK antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Recombinant protein encompassing a sequence within the center region of human ZAK. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HeLa

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.92 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ZAK

Antigène: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Autre désignation: mitogen-activated protein kinase kinase kinase 20 (ZAK Produits)

Synonymes: anticorps MLTK, anticorps RGD1561394, anticorps AZK, anticorps MLK7, anticorps MLT, anticorps MRK, anticorps mlklak, anticorps pk, anticorps AV006891, anticorps B230120H23Rik, anticorps MLTKalpha, anticorps MLTKbeta, anticorps mitogen-activated protein kinase kinase kinase 20, anticorps Map3k20, anticorps MAP3K20

Sujet: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Cellular Localization: Cytoplasm , Nucleus

Poids moléculaire: 91 kDa

ID gène: 51776

UniProt: Q9NYL2