GSTM5 anticorps
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- Antigène Voir toutes GSTM5 Anticorps
- GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GSTM5 est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Souris
- Attributs du produit
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Rabbit Polyclonal antibody to GSTM5 (glutathione S-transferase mu 5)
GSTM5 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human GSTM5. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product GSTM5 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: Mouse brain
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))
- Autre désignation
- glutathione S-transferase mu 5 (GSTM5 Produits)
- Synonymes
- anticorps GSTM5-5, anticorps GTM5, anticorps glutathione S-transferase mu 5, anticorps glutathione S-transferase, mu 5, anticorps GSTM5, anticorps Gstm5
- Sujet
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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.
Cellular Localization: Cytoplasm - Poids moléculaire
- 26 kDa
- ID gène
- 2949
- UniProt
- P46439
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